Glass reactor systems 5 - 250 liter

Modular glass reactor systems for process development, kilo labs and pilot plant scale-up, from full vacuum up to +0.5 bar. Made of highly corrosion-resistant materials including borosilicate glass 3.3 and glass-lined steel and built with the proprietary buchiflex flexible glass piping system for leak-tight, stress-free operation. Full compliance with cGMP requirements and regulations such as ATEX and PED.

Nutsche filters 10 - 300 liter

Solid-liquid separation for kilo labs, pilot plants / scale-up and small-scale production. Effortless operation and cake removal thanks to lifting devices, tilting mechanism and removable filter cloths. Glass nutsche filters operate from full vacuum up to +0.5 bar, pressure nutsche filters in stainless steel or Hastelloy® handle demanding applications up to 6 bar. Full compliance with cGMP requirements and regulations such as ATEX and PED.

Peptide synthesizers 5 – 500 liter

Solid-phase peptide synthesizers for process development, kilo labs and small-scale peptide API manufacturing. Jacketed vessels allow for precise temperature control, state of the art designed agitators gently suspend resins and reagents, and integrated bottom filtration streamlines washing and cleavage. Built from borosilicate glass 3.3, fluoropolymer coated stainless steel or Hastelloy® and tailored according to your process requirements. Full compliance with cGMP requirements and regulations such as ATEX and PED.

HPAPI reactor & process systems

High containment glass reactor systems for safe handling and synthesis of highly potent APIs (HPAPIs) in process development, kilo labs and small-scale production. Compact footprints fit isolators and glove boxes, CIP spray nozzles enable residue-free cleaning, and with split valves to minimize exposure (OEL/OEB). Fully customized and engineered according to your operational requirements and smartly integrated into glove boxes & isolators. Full compliance with cGMP requirements and regulations such as ATEX and PED.

Filter reactors for pilot plants and kilo labs

Multipurpose filter reactors that combine synthesis, crystallization / purification in one system. Features include removable filter cloths, heating jackets and heated bottom plates for efficient and optimized heat transfer during any process. Built from borosilicate glass 3.3, fluoropolymer coated stainless steel or Hastelloy® and tailored according to your process requirements. Full compliance with cGMP requirements and regulations such as ATEX and PED.

Process equipment > 250 liter

Glass-lined steel reactors from 250 to 10000 liter combined with customized glass distillation and rectification systems (glass distillation overheads) for commercial chemical manufacturing. Separation & rectification (glass) columns and stationary gas scrubbers complete the process equipment offering. Built from borosilicate glass 3.3, glass-lined steel, fluoropolymers and Hastelloy® and tailored according to your process requirements. Highly corrosion resistant heat exchangers made of high-performance materials guarantee stable process conditions and a long service life. Full compliance with cGMP requirements and regulations such as ATEX and PED.

Mixing vessel, storage tanks 10 - 400 liter

Glass mixing vessels and storage tanks, jacketed (10 – 100 liter) or non-jacketed (10 – 400 liter), for work-up, preparation and intermediate storage. Highly corrosion resistant and in full compliance with cGMP requirements and regulations such as ATEX and PED.

Gas scrubber mobile 10 - 100 liter

Mobile gas scrubbers from 10 to 100 liter for laboratory, kilo lab / pilot plants and small-scale production. Efficient and economical solution for neutralizing corrosive exhaust gases. The gas scrubbers operate from full vacuum up to +0.5 bar at exhaust gas temperatures from -60 °C to +200 °C. Full compliance with regulations such as ATEX and PED.

Features and auxiliary equipment

Measuring & control devices

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Büchi AG - buchiglasuster® - Reactor Systems and Pilot Plants for the chemical and pharma industry

Buchi midiPilot - glass reactor