Filter reactors for pilot plants and kilo labs 10

Buchi Filter reactor FR 30

Filter reactors for pilot plants and kilo labs

Filtration vessel:	10, 30, 50 liter
Pressure FR 10:	-1.0 (FV) to +1.0 bar
Pressure FR 30, FR 50:	-1.0 (FV) to +0.5 bar
Temperature:	-60/+200 °C

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Typical applications

Chemical synthesis
Cannabis solvent extraction
Evaporation / precipitation / crystallization
Scale-up
Filtration / washing / drying
Solid phase peptide synthesis (SPPS)
cGMP API production

About the filter reactor

Our innovative filter reactors are specifically designed for pilot plants and kilo laboratories. These systems combine a reactor and a nutsche filter in a single unit, enabling a wide range of processes and applications, including cGMP API synthesis, peptide synthesis (peptide synthesizer), and cannabis extraction.

The filter reactors are available in three sizes, with 10 liter, 30 liter, and 50 liter reaction volumes. They feature a modular design that allows for easy configuration to meet your specific process requirements.

Our filter reactor systems are distinguished by Swiss Quality, safety, and reliability. They are modular, compact, and mobile, allowing for flexible handling and versatile applications. The straightforward operation and the ability to perform various processes in a single device make them particularly user-friendly.

These systems are turnkey, highly corrosion-resistant, and inert, making them ideal for demanding applications in laboratories and production. Certified to ATEX, CE, and cGMP standards, they offer the highest levels of safety and quality.

BACK TO PRODUCT OVERVIEW

Complete, ready-to-run setup for reaction, filtration, and cake discharge.

Reaction vessel: Borosilicate glass 3.3 with integrated heating/cooling jacket
Structure & sealing: Durable cover plate and bottom plate made from stainless steel with PFA coating
Drive & agitation: Dry-running mechanical seal with ATEX-certified stirrer drive
Mixing system: Multi-stage stirrer and baffle with integrated Pt100 temperature sensor (PFA coated)
Cake discharge: Manual 2-step lowering device for vessel and bottom plate with swing-out mechanism
Connectivity: Pull-safe TCU connection ports, heating hoses, and flexible, vacuum-tight buchiflex glass piping

Customized options for your process requirements, including but not limited to:

Glass overhead: 4 modular glass upper section (GUS) configurations or fully customized designs
Material upgrades: Cover plate, bottom plate, and stirrer available in stainless steel 1.4404 or Hastelloy® C22
Thermal filtercake drying: Heated bottom plate for improved heat transfer (stainless steel 1.4404 or Hastelloy® C22)
Process monitoring & control: Integration of sensors for temperature, pressure/vacuum, stirrer speed, and pH
Liquid handling & peptide synthesis: Automated reagent dosing and solvent washing steps for solid-phase synthesis (SPPS)
Process sampling: Sampling device
Cleanroom & cleaning: Cleanroom design for highly potent active pharmaceutical ingredients (HPAPIs) and CIP spray nozzle

Connection set: For inert gas blanketing (N₂), venting, and direct liquid transfer during closed filtration under full vacuum to overpressure.

Reflux-Basic: Vertical condenser cover plate, designed for condensation and returning evaporated solvent back into the filter reactor.

Reflux: Active reflux condensation paired with a graduated feeding vessel for controlled liquid dosing during synthesis.

Multipurpose: Glas overhead setup combining a horizontal condenser, dosing vessel, receiver flask, and phase separator for solvent recovery, distillation, and liquid-liquid extraction.